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Neurological manifestations and complications of COVID-19: A literature review

The Coronavirus disease due to SARS-CoV-2 emerged in Wuhan city, China in December 2019 and rapidly spread to more than 200 countries as a global health pandemic. There are more than 3.5 million confirmed cases and around 165,000 to 243,000 fatalities. The primary manifestation is respiratory and ca...

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Detalles Bibliográficos
Autores principales: Ahmad, Imran, Rathore, Farooq Azam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200361/
https://www.ncbi.nlm.nih.gov/pubmed/32409215
http://dx.doi.org/10.1016/j.jocn.2020.05.017
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author Ahmad, Imran
Rathore, Farooq Azam
author_facet Ahmad, Imran
Rathore, Farooq Azam
author_sort Ahmad, Imran
collection PubMed
description The Coronavirus disease due to SARS-CoV-2 emerged in Wuhan city, China in December 2019 and rapidly spread to more than 200 countries as a global health pandemic. There are more than 3.5 million confirmed cases and around 165,000 to 243,000 fatalities. The primary manifestation is respiratory and cardiac but neurological features are also being reported in the literature as case reports and case series. The most common reported symptoms to include headache and dizziness followed by encephalopathy and delirium. Among the complications noted are Cerebrovascular accident, Guillian barre syndrome, acute transverse myelitis, and acute encephalitis. The most common peripheral manifestation was hyposmia. It is further noted that sometimes the neurological manifestations can precede the typical features like fever and cough and later on typical manifestations develop in these patients. Hence a high index of suspicion is required for timely diagnosis and isolation of cases to prevent the spread in neurology wards. We present a narrative review of the neurological manifestations and complications of COVID-19. Our aim is to update the neurologists and physicians working with suspected cases of COVID-19 about the possible neurological presentations and the probable neurological complications resulting from this novel virus infection.
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spelling pubmed-72003612020-05-06 Neurological manifestations and complications of COVID-19: A literature review Ahmad, Imran Rathore, Farooq Azam J Clin Neurosci Article The Coronavirus disease due to SARS-CoV-2 emerged in Wuhan city, China in December 2019 and rapidly spread to more than 200 countries as a global health pandemic. There are more than 3.5 million confirmed cases and around 165,000 to 243,000 fatalities. The primary manifestation is respiratory and cardiac but neurological features are also being reported in the literature as case reports and case series. The most common reported symptoms to include headache and dizziness followed by encephalopathy and delirium. Among the complications noted are Cerebrovascular accident, Guillian barre syndrome, acute transverse myelitis, and acute encephalitis. The most common peripheral manifestation was hyposmia. It is further noted that sometimes the neurological manifestations can precede the typical features like fever and cough and later on typical manifestations develop in these patients. Hence a high index of suspicion is required for timely diagnosis and isolation of cases to prevent the spread in neurology wards. We present a narrative review of the neurological manifestations and complications of COVID-19. Our aim is to update the neurologists and physicians working with suspected cases of COVID-19 about the possible neurological presentations and the probable neurological complications resulting from this novel virus infection. Elsevier Ltd. 2020-07 2020-05-06 /pmc/articles/PMC7200361/ /pubmed/32409215 http://dx.doi.org/10.1016/j.jocn.2020.05.017 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Ahmad, Imran
Rathore, Farooq Azam
Neurological manifestations and complications of COVID-19: A literature review
title Neurological manifestations and complications of COVID-19: A literature review
title_full Neurological manifestations and complications of COVID-19: A literature review
title_fullStr Neurological manifestations and complications of COVID-19: A literature review
title_full_unstemmed Neurological manifestations and complications of COVID-19: A literature review
title_short Neurological manifestations and complications of COVID-19: A literature review
title_sort neurological manifestations and complications of covid-19: a literature review
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200361/
https://www.ncbi.nlm.nih.gov/pubmed/32409215
http://dx.doi.org/10.1016/j.jocn.2020.05.017
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