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Estimating the COVID-19 infection rate: Anatomy of an inference problem

As a consequence of missing data on tests for infection and imperfect accuracy of tests, reported rates of cumulative population infection by the SARS CoV-2 virus are lower than actual rates of infection. Hence, reported rates of severe illness conditional on infection are higher than actual rates....

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Autores principales: Manski, Charles F., Molinari, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200382/
https://www.ncbi.nlm.nih.gov/pubmed/32377030
http://dx.doi.org/10.1016/j.jeconom.2020.04.041
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author Manski, Charles F.
Molinari, Francesca
author_facet Manski, Charles F.
Molinari, Francesca
author_sort Manski, Charles F.
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description As a consequence of missing data on tests for infection and imperfect accuracy of tests, reported rates of cumulative population infection by the SARS CoV-2 virus are lower than actual rates of infection. Hence, reported rates of severe illness conditional on infection are higher than actual rates. Understanding the time path of the COVID-19 pandemic has been hampered by the absence of bounds on infection rates that are credible and informative. This paper explains the logical problem of bounding these rates and reports illustrative findings, using data from Illinois, New York, and Italy. We combine the data with assumptions on the infection rate in the untested population and on the accuracy of the tests that appear credible in the current context. We find that the infection rate might be substantially higher than reported. We also find that, assuming accurate reporting of deaths, the infection fatality rates in Illinois, New York, and Italy are substantially lower than reported.
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spelling pubmed-72003822020-05-06 Estimating the COVID-19 infection rate: Anatomy of an inference problem Manski, Charles F. Molinari, Francesca J Econom Article As a consequence of missing data on tests for infection and imperfect accuracy of tests, reported rates of cumulative population infection by the SARS CoV-2 virus are lower than actual rates of infection. Hence, reported rates of severe illness conditional on infection are higher than actual rates. Understanding the time path of the COVID-19 pandemic has been hampered by the absence of bounds on infection rates that are credible and informative. This paper explains the logical problem of bounding these rates and reports illustrative findings, using data from Illinois, New York, and Italy. We combine the data with assumptions on the infection rate in the untested population and on the accuracy of the tests that appear credible in the current context. We find that the infection rate might be substantially higher than reported. We also find that, assuming accurate reporting of deaths, the infection fatality rates in Illinois, New York, and Italy are substantially lower than reported. Elsevier B.V. 2021-01 2020-05-06 /pmc/articles/PMC7200382/ /pubmed/32377030 http://dx.doi.org/10.1016/j.jeconom.2020.04.041 Text en © 2020 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Manski, Charles F.
Molinari, Francesca
Estimating the COVID-19 infection rate: Anatomy of an inference problem
title Estimating the COVID-19 infection rate: Anatomy of an inference problem
title_full Estimating the COVID-19 infection rate: Anatomy of an inference problem
title_fullStr Estimating the COVID-19 infection rate: Anatomy of an inference problem
title_full_unstemmed Estimating the COVID-19 infection rate: Anatomy of an inference problem
title_short Estimating the COVID-19 infection rate: Anatomy of an inference problem
title_sort estimating the covid-19 infection rate: anatomy of an inference problem
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200382/
https://www.ncbi.nlm.nih.gov/pubmed/32377030
http://dx.doi.org/10.1016/j.jeconom.2020.04.041
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