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scAAV2-Mediated C3 Transferase Gene Therapy in a Rat Model with Retinal Ischemia/Reperfusion Injuries

Glaucoma is characterized by retinal ganglion cell (RGC) death and axonal loss. Therefore, neuroprotection is important in treating glaucoma. In this study, we explored whether exoenzyme C3 transferase (C3)-based gene therapy could protect retinas in an ischemia/reperfusion (I/R) injury rat model. S...

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Detalles Bibliográficos
Autores principales:	Tan, Junkai, Zhang, Xiaoguang, Li, Danli, Liu, Guo, Wang, Yun, Zhang, Daren, Wang, Xizhen, Tian, Wenhong, Dong, Xiaoyan, Zhou, Liang, Zhu, Xianjun, Liu, Xuyang, Fan, Ning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200613/ https://www.ncbi.nlm.nih.gov/pubmed/32382585 http://dx.doi.org/10.1016/j.omtm.2020.04.014

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