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Stumbling upon the unexpected: A unique presentation of phosphaturic mesenchymal tumor in the hindfoot
We describe an unexpected and unique case of phosphaturic mesenchymal tumor in a 38-year-old female presenting with a painful lump in the plantar hindfoot. Phosphaturic mesenchymal tumors are extremely rare, generally benign soft tissue or osseous tumors, which are associated with overexpression of...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200620/ https://www.ncbi.nlm.nih.gov/pubmed/32382367 http://dx.doi.org/10.1016/j.radcr.2020.04.024 |
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author | El-Karim, Ghassan Awad Almalki, Youssef Alolabi, Bashar |
author_facet | El-Karim, Ghassan Awad Almalki, Youssef Alolabi, Bashar |
author_sort | El-Karim, Ghassan Awad |
collection | PubMed |
description | We describe an unexpected and unique case of phosphaturic mesenchymal tumor in a 38-year-old female presenting with a painful lump in the plantar hindfoot. Phosphaturic mesenchymal tumors are extremely rare, generally benign soft tissue or osseous tumors, which are associated with overexpression of fibroblast growth factor-23 and tumor-associated osteomalacia. Patients often present with progressive signs and symptoms including systemic bone pain, muscle weakness, and insufficiency fractures, and timely diagnosis is paramount to appropriate therapy. Tumor resection is almost always curative with normalization of laboratory markers and resolution of symptomatology. |
format | Online Article Text |
id | pubmed-7200620 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-72006202020-05-07 Stumbling upon the unexpected: A unique presentation of phosphaturic mesenchymal tumor in the hindfoot El-Karim, Ghassan Awad Almalki, Youssef Alolabi, Bashar Radiol Case Rep Musculoskeletal We describe an unexpected and unique case of phosphaturic mesenchymal tumor in a 38-year-old female presenting with a painful lump in the plantar hindfoot. Phosphaturic mesenchymal tumors are extremely rare, generally benign soft tissue or osseous tumors, which are associated with overexpression of fibroblast growth factor-23 and tumor-associated osteomalacia. Patients often present with progressive signs and symptoms including systemic bone pain, muscle weakness, and insufficiency fractures, and timely diagnosis is paramount to appropriate therapy. Tumor resection is almost always curative with normalization of laboratory markers and resolution of symptomatology. Elsevier 2020-04-30 /pmc/articles/PMC7200620/ /pubmed/32382367 http://dx.doi.org/10.1016/j.radcr.2020.04.024 Text en © 2020 The Authors. Published by Elsevier Inc. on behalf of University of Washington. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Musculoskeletal El-Karim, Ghassan Awad Almalki, Youssef Alolabi, Bashar Stumbling upon the unexpected: A unique presentation of phosphaturic mesenchymal tumor in the hindfoot |
title | Stumbling upon the unexpected: A unique presentation of phosphaturic mesenchymal tumor in the hindfoot |
title_full | Stumbling upon the unexpected: A unique presentation of phosphaturic mesenchymal tumor in the hindfoot |
title_fullStr | Stumbling upon the unexpected: A unique presentation of phosphaturic mesenchymal tumor in the hindfoot |
title_full_unstemmed | Stumbling upon the unexpected: A unique presentation of phosphaturic mesenchymal tumor in the hindfoot |
title_short | Stumbling upon the unexpected: A unique presentation of phosphaturic mesenchymal tumor in the hindfoot |
title_sort | stumbling upon the unexpected: a unique presentation of phosphaturic mesenchymal tumor in the hindfoot |
topic | Musculoskeletal |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200620/ https://www.ncbi.nlm.nih.gov/pubmed/32382367 http://dx.doi.org/10.1016/j.radcr.2020.04.024 |
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