Cargando…

Stumbling upon the unexpected: A unique presentation of phosphaturic mesenchymal tumor in the hindfoot

We describe an unexpected and unique case of phosphaturic mesenchymal tumor in a 38-year-old female presenting with a painful lump in the plantar hindfoot. Phosphaturic mesenchymal tumors are extremely rare, generally benign soft tissue or osseous tumors, which are associated with overexpression of...

Descripción completa

Detalles Bibliográficos
Autores principales: El-Karim, Ghassan Awad, Almalki, Youssef, Alolabi, Bashar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200620/
https://www.ncbi.nlm.nih.gov/pubmed/32382367
http://dx.doi.org/10.1016/j.radcr.2020.04.024
_version_ 1783529372667346944
author El-Karim, Ghassan Awad
Almalki, Youssef
Alolabi, Bashar
author_facet El-Karim, Ghassan Awad
Almalki, Youssef
Alolabi, Bashar
author_sort El-Karim, Ghassan Awad
collection PubMed
description We describe an unexpected and unique case of phosphaturic mesenchymal tumor in a 38-year-old female presenting with a painful lump in the plantar hindfoot. Phosphaturic mesenchymal tumors are extremely rare, generally benign soft tissue or osseous tumors, which are associated with overexpression of fibroblast growth factor-23 and tumor-associated osteomalacia. Patients often present with progressive signs and symptoms including systemic bone pain, muscle weakness, and insufficiency fractures, and timely diagnosis is paramount to appropriate therapy. Tumor resection is almost always curative with normalization of laboratory markers and resolution of symptomatology.
format Online
Article
Text
id pubmed-7200620
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-72006202020-05-07 Stumbling upon the unexpected: A unique presentation of phosphaturic mesenchymal tumor in the hindfoot El-Karim, Ghassan Awad Almalki, Youssef Alolabi, Bashar Radiol Case Rep Musculoskeletal We describe an unexpected and unique case of phosphaturic mesenchymal tumor in a 38-year-old female presenting with a painful lump in the plantar hindfoot. Phosphaturic mesenchymal tumors are extremely rare, generally benign soft tissue or osseous tumors, which are associated with overexpression of fibroblast growth factor-23 and tumor-associated osteomalacia. Patients often present with progressive signs and symptoms including systemic bone pain, muscle weakness, and insufficiency fractures, and timely diagnosis is paramount to appropriate therapy. Tumor resection is almost always curative with normalization of laboratory markers and resolution of symptomatology. Elsevier 2020-04-30 /pmc/articles/PMC7200620/ /pubmed/32382367 http://dx.doi.org/10.1016/j.radcr.2020.04.024 Text en © 2020 The Authors. Published by Elsevier Inc. on behalf of University of Washington. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Musculoskeletal
El-Karim, Ghassan Awad
Almalki, Youssef
Alolabi, Bashar
Stumbling upon the unexpected: A unique presentation of phosphaturic mesenchymal tumor in the hindfoot
title Stumbling upon the unexpected: A unique presentation of phosphaturic mesenchymal tumor in the hindfoot
title_full Stumbling upon the unexpected: A unique presentation of phosphaturic mesenchymal tumor in the hindfoot
title_fullStr Stumbling upon the unexpected: A unique presentation of phosphaturic mesenchymal tumor in the hindfoot
title_full_unstemmed Stumbling upon the unexpected: A unique presentation of phosphaturic mesenchymal tumor in the hindfoot
title_short Stumbling upon the unexpected: A unique presentation of phosphaturic mesenchymal tumor in the hindfoot
title_sort stumbling upon the unexpected: a unique presentation of phosphaturic mesenchymal tumor in the hindfoot
topic Musculoskeletal
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200620/
https://www.ncbi.nlm.nih.gov/pubmed/32382367
http://dx.doi.org/10.1016/j.radcr.2020.04.024
work_keys_str_mv AT elkarimghassanawad stumblingupontheunexpectedauniquepresentationofphosphaturicmesenchymaltumorinthehindfoot
AT almalkiyoussef stumblingupontheunexpectedauniquepresentationofphosphaturicmesenchymaltumorinthehindfoot
AT alolabibashar stumblingupontheunexpectedauniquepresentationofphosphaturicmesenchymaltumorinthehindfoot