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Radiation-Induced DNMT3B Promotes Radioresistance in Nasopharyngeal Carcinoma through Methylation of p53 and p21

Radiotherapy with or without concurrent chemotherapy is the standard treatment for nasopharyngeal carcinoma (NPC) patients, whose efficacy is limited partly by intrinsic and acquired radioresistance. DNA methyltransferase 3B (DNMT3B) has been reported to participate in tumorigenesis via DNA methylat...

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Detalles Bibliográficos
Autores principales:	Wu, Cheng, Guo, Ergang, Ming, Jun, Sun, Wei, Nie, Xin, Sun, Lu, Peng, Shan, Luo, Min, Liu, Dongbo, Zhang, Linli, Mei, Qi, Long, Guoxian, Hu, Guangyuan, Hu, Guoqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200625/ https://www.ncbi.nlm.nih.gov/pubmed/32382655 http://dx.doi.org/10.1016/j.omto.2020.04.007

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