Allelic variants between mouse substrains BALB/cJ and BALB/cByJ influence mononuclear cardiomyocyte composition and cardiomyocyte nuclear ploidy

Most mouse cardiomyocytes (CMs) become multinucleated shortly after birth via endoreplication and interrupted mitosis, which persists through adulthood. The very closely related inbred mouse strains BALB/cJ and BALB/cByJ differ substantially (6.6% vs. 14.3%) in adult mononuclear CM level. This diffe...

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Detalles Bibliográficos
Autores principales: Gan, Peiheng, Patterson, Michaela, Watanabe, Hirofumi, Wang, Kristy, Edmonds, Reilly A., Reinholdt, Laura G., Sucov, Henry M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200697/
https://www.ncbi.nlm.nih.gov/pubmed/32371981
http://dx.doi.org/10.1038/s41598-020-64621-0

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