Cargando…

Long-range Regulation of Partially Folded Amyloidogenic Peptides

Neurodegeneration involves abnormal aggregation of intrinsically disordered amyloidogenic peptides (IDPs), usually mediated by hydrophobic protein-protein interactions. There is mounting evidence that formation of α-helical intermediates is an early event during self-assembly of amyloid-β42 (Aβ42) a...

Descripción completa

Detalles Bibliográficos
Autores principales: Bhattacharya, Shayon, Xu, Liang, Thompson, Damien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200734/
https://www.ncbi.nlm.nih.gov/pubmed/32371882
http://dx.doi.org/10.1038/s41598-020-64303-x