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Long-range Regulation of Partially Folded Amyloidogenic Peptides
Neurodegeneration involves abnormal aggregation of intrinsically disordered amyloidogenic peptides (IDPs), usually mediated by hydrophobic protein-protein interactions. There is mounting evidence that formation of α-helical intermediates is an early event during self-assembly of amyloid-β42 (Aβ42) a...
Autores principales: | Bhattacharya, Shayon, Xu, Liang, Thompson, Damien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200734/ https://www.ncbi.nlm.nih.gov/pubmed/32371882 http://dx.doi.org/10.1038/s41598-020-64303-x |
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