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In-vitro safety and off-target profile of the anti-parasitic arylmethylaminosteroid 1o

Parasite-mediated diseases like malaria and schistosomiasis are growing health problems worldwide and novel drug candidates are urgently needed. In this study, the in-vitro safety profile of steroid compound 1o (sc1o), effective against the parasites Plasmodium falciparum and Schistosoma mansoni wit...

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Detalles Bibliográficos
Autores principales: Blum, Leonard, Gul, Sheraz, Ulshöfer, Thomas, Henke, Marina, Krieg, Reimar, Berneburg, Isabell, Thomas, Dominique, Trautmann, Sandra, Kurz, Jennifer, Geyer, Joachim, Geisslinger, Gerd, Becker, Katja, Parnham, Michael J., Schiffmann, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200784/
https://www.ncbi.nlm.nih.gov/pubmed/32371995
http://dx.doi.org/10.1038/s41598-020-64382-w