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Repurposing approach identifies pitavastatin as a potent azole chemosensitizing agent effective against azole-resistant Candida species

The limited number of antifungals and the rising frequency of azole-resistant Candida species are growing challenges to human medicine. Drug repurposing signifies an appealing approach to enhance the activity of current antifungal drugs. Here, we evaluated the ability of Pharmakon 1600 drug library...

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Detalles Bibliográficos
Autores principales:	Eldesouky, Hassan E., Salama, Ehab A., Li, Xiaoyan, Hazbun, Tony R., Mayhoub, Abdelrahman S., Seleem, Mohamed N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200796/ https://www.ncbi.nlm.nih.gov/pubmed/32372011 http://dx.doi.org/10.1038/s41598-020-64571-7

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