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Genome editing in the nematode Caenorhabditis briggsae using the CRISPR/Cas9 system

The CRISPR/Cas system has recently emerged as a powerful tool to engineer the genome of an organism. The system is adopted from bacteria where it confers immunity against invading foreign DNA. This work reports the first successful use of the CRISPR/Cas system in Caenorhabditis briggsae (a cousin of...

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Detalles Bibliográficos
Autores principales: Culp, Elizabeth, Richman, Cory, Sharanya, Devika, Jhaveri, Nikita, van den Berg, Wouter, Gupta, Bhagwati P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200835/
https://www.ncbi.nlm.nih.gov/pubmed/32395632
http://dx.doi.org/10.1093/biomethods/bpaa003