Molecular Mechanisms of Trophoblast Dysfunction Mediated by Imbalance between STOX1 Isoforms

STOX1 is a transcription factor involved in preeclampsia and Alzheimer disease. We show that the knock-down of the gene induces rather mild effect on gene expression in trophoblast cell lines (BeWo). We identified binding sites of STOX1 shared by the two major isoforms, STOX1A and STOX1B. Profiling...

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Detalles Bibliográficos
Autores principales: Ducat, Aurélien, Couderc, Betty, Bouter, Anthony, Biquard, Louise, Aouache, Rajaa, Passet, Bruno, Doridot, Ludivine, Cohen, Marie-Benoîte, Ribaux, Pascale, Apicella, Clara, Gaillard, Irène, Palfray, Sophia, Chen, Yulian, Vargas, Alexandra, Julé, Amélie, Frelin, Léo, Cocquet, Julie, San Martin, Camino Ruano, Jacques, Sébastien, Busato, Florence, Tost, Jorg, Méhats, Céline, Laissue, Paul, Vilotte, Jean-Luc, Miralles, Francisco, Vaiman, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200942/
https://www.ncbi.nlm.nih.gov/pubmed/32371375
http://dx.doi.org/10.1016/j.isci.2020.101086

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