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Tumor Mutation Burden Correlates With Efficacy of Chemotherapy/Targeted Therapy in Advanced Non–Small Cell Lung Cancer
Objectives: Accumulating evidence has illustrated greater benefit of immunotherapy in tumors with high tumor mutation burden (TMB), whereas its impact on targeted therapy or chemotherapy is undefined. Herein, we evaluated TMB outside of immuno-oncology in epidermal growth factor receptor (EGFR)–muta...
Autores principales: | Lin, Chen, Shi, Xun, Zhao, Jun, He, Qiong, Fan, Yun, Xu, Weizhen, Shao, Yang, Yu, Xinmin, Jin, Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201001/ https://www.ncbi.nlm.nih.gov/pubmed/32411590 http://dx.doi.org/10.3389/fonc.2020.00480 |
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