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Optimal age for genetic cancer predisposition testing in hereditary SMARCA4 Ovarian Cancer Families: How young is too young?
Small cell carcinoma of the ovary, hypercalcemic type is a rare, aggressive, and typically fatal ovarian cancer that primarily affects young women less than 40 years of age. It is caused by a pathogenic variant in the SMARCA4 gene, with nearly half of patients found to have germline pathogenic varia...
Autores principales: | Podwika, Sarah E., Jenkins, Taylor M., Khokhar, Joyti K., Erickson, Sarah H., Modesitt, Susan C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201186/ https://www.ncbi.nlm.nih.gov/pubmed/32382648 http://dx.doi.org/10.1016/j.gore.2020.100569 |
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