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Targeting Pyruvate Carboxylase by a Small Molecule Suppresses Breast Cancer Progression

Rapid metabolism differentiates cancer cells from normal cells and relies on anaplerotic pathways. However, the mechanisms of anaplerosis‐associated enzymes are rarely understood. The lack of potent and selective antimetabolism drugs restrains further clinical investigations. A small molecule ZY‐444...

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Detalles Bibliográficos
Autores principales:	Lin, Qingxiang, He, Yuan, Wang, Xue, Zhang, Yong, Hu, Meichun, Guo, Weikai, He, Yundong, Zhang, Tao, Lai, Li, Sun, Zhenliang, Yi, Zhengfang, Liu, Mingyao, Chen, Yihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201266/ https://www.ncbi.nlm.nih.gov/pubmed/32382484 http://dx.doi.org/10.1002/advs.201903483

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