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A structural study of TatD from Staphylococcus aureus elucidates a putative DNA-binding mode of a Mg(2+)-dependent nuclease

TatD has been thoroughly investigated as a DNA-repair enzyme and an apoptotic nuclease, and still-unknown TatD-related DNases are considered to play crucial cellular roles. However, studies of TatD from Gram-positive bacteria have been hindered by an absence of atomic detail and the resulting inabil...

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Detalles Bibliográficos
Autores principales: Lee, Kyu-Yeon, Cheon, Seung-Ho, Kim, Dong-Gyun, Lee, Sang Jae, Lee, Bong-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201278/
https://www.ncbi.nlm.nih.gov/pubmed/32431834
http://dx.doi.org/10.1107/S2052252520003917