Whole-genome mate-pair sequencing of apparently balanced chromosome rearrangements reveals complex structural variations: two case studies

BACKGROUND: Apparently balanced chromosome rearrangements (ABCRs) in non-affected individuals are well-known to possess high reproductive risks such as infertility, abnormal offspring, and pregnancy loss. However, caution should be exercised in genetic counseling and reproductive intervention becaus...

Descripción completa

Detalles Bibliográficos
Autores principales: Tan, Ya-Qi, Tan, Yue-Qiu, Cheng, De-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201554/
https://www.ncbi.nlm.nih.gov/pubmed/32391085
http://dx.doi.org/10.1186/s13039-020-00487-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201554/
https://www.ncbi.nlm.nih.gov/pubmed/32391085
http://dx.doi.org/10.1186/s13039-020-00487-1

Ejemplares similares