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Evidence for dimerization of ferroportin in a human hepatic cell line using proximity ligation assays

Mutations in the only known iron exporter ferroportin (FPN) in humans are associated with the autosomal dominantly inherited iron overload disorder ferroportin disease or type IV hereditary hemochromatosis (HH). While our knowledge of the central role of FPN in iron homeostasis has grown in the last...

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Detalles Bibliográficos
Autores principales: Rishi, Gautam, Secondes, Eriza S., Wallace, Daniel F., Subramaniam, V. Nathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201565/
https://www.ncbi.nlm.nih.gov/pubmed/32301493
http://dx.doi.org/10.1042/BSR20191499