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Rational dispensing of oral dosage forms of medicines to children at a teaching hospital in Sri Lanka

BACKGROUND: Good dispensing practice is vital for rational use of medicines. There are many paediatric specific challenges when maintaining good dispensing practices to children. Lack of age appropriate dosage forms, lack of medicines in strengths suitable for children, lack of palatable medicines,...

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Autores principales: Nadeshkumar, Abarna, Sathiadas, Gitanjali, Sri Ranganathan, Shalini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201638/
https://www.ncbi.nlm.nih.gov/pubmed/32375749
http://dx.doi.org/10.1186/s12913-020-05246-x
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author Nadeshkumar, Abarna
Sathiadas, Gitanjali
Sri Ranganathan, Shalini
author_facet Nadeshkumar, Abarna
Sathiadas, Gitanjali
Sri Ranganathan, Shalini
author_sort Nadeshkumar, Abarna
collection PubMed
description BACKGROUND: Good dispensing practice is vital for rational use of medicines. There are many paediatric specific challenges when maintaining good dispensing practices to children. Lack of age appropriate dosage forms, lack of medicines in strengths suitable for children, lack of palatable medicines, lack of expertise in paediatric pharmacy are few challenges faced when maintaining good dispensing practices to children. These challenges contribute to poor dispensing practices. Hence there is an urgent need to investigate whether oral dosage forms of medicines are dispensed rationally to children. The objective of this study was to describe the rational dispensing practice of oral dosage forms of medicines to children in a Teaching Hospital in Sri Lanka. METHODS: A descriptive cross sectional study was conducted to assess the dispensing practice of 1800 oral dosage forms of medicines dispensed to children under the age of 12 years in two outdoor pharmacies over a period of 1 year using validated indicators. Required data were extracted from the prescriptions and by observation using a structured pre-tested observation sheet. Descriptive statistics and wherever relevant, chi square test were used in analysing the data. RESULTS: Information on 1800 oral dosage forms was obtained from 1889 medicines dispensed to 727 children. Liquids were 52% [95% CI: 50–55%] of these oral dosage forms. Of the solid dosage forms, about one quarter required manipulation prior to administration such as splitting and dissolving or crushing the adult dosage form. None of the medicine packs or bottles had the patient name on the label. CONCLUSION: Dispensing practice of oral dosage forms of medicines to children has room for improvement.
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spelling pubmed-72016382020-05-08 Rational dispensing of oral dosage forms of medicines to children at a teaching hospital in Sri Lanka Nadeshkumar, Abarna Sathiadas, Gitanjali Sri Ranganathan, Shalini BMC Health Serv Res Research Article BACKGROUND: Good dispensing practice is vital for rational use of medicines. There are many paediatric specific challenges when maintaining good dispensing practices to children. Lack of age appropriate dosage forms, lack of medicines in strengths suitable for children, lack of palatable medicines, lack of expertise in paediatric pharmacy are few challenges faced when maintaining good dispensing practices to children. These challenges contribute to poor dispensing practices. Hence there is an urgent need to investigate whether oral dosage forms of medicines are dispensed rationally to children. The objective of this study was to describe the rational dispensing practice of oral dosage forms of medicines to children in a Teaching Hospital in Sri Lanka. METHODS: A descriptive cross sectional study was conducted to assess the dispensing practice of 1800 oral dosage forms of medicines dispensed to children under the age of 12 years in two outdoor pharmacies over a period of 1 year using validated indicators. Required data were extracted from the prescriptions and by observation using a structured pre-tested observation sheet. Descriptive statistics and wherever relevant, chi square test were used in analysing the data. RESULTS: Information on 1800 oral dosage forms was obtained from 1889 medicines dispensed to 727 children. Liquids were 52% [95% CI: 50–55%] of these oral dosage forms. Of the solid dosage forms, about one quarter required manipulation prior to administration such as splitting and dissolving or crushing the adult dosage form. None of the medicine packs or bottles had the patient name on the label. CONCLUSION: Dispensing practice of oral dosage forms of medicines to children has room for improvement. BioMed Central 2020-05-06 /pmc/articles/PMC7201638/ /pubmed/32375749 http://dx.doi.org/10.1186/s12913-020-05246-x Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Nadeshkumar, Abarna
Sathiadas, Gitanjali
Sri Ranganathan, Shalini
Rational dispensing of oral dosage forms of medicines to children at a teaching hospital in Sri Lanka
title Rational dispensing of oral dosage forms of medicines to children at a teaching hospital in Sri Lanka
title_full Rational dispensing of oral dosage forms of medicines to children at a teaching hospital in Sri Lanka
title_fullStr Rational dispensing of oral dosage forms of medicines to children at a teaching hospital in Sri Lanka
title_full_unstemmed Rational dispensing of oral dosage forms of medicines to children at a teaching hospital in Sri Lanka
title_short Rational dispensing of oral dosage forms of medicines to children at a teaching hospital in Sri Lanka
title_sort rational dispensing of oral dosage forms of medicines to children at a teaching hospital in sri lanka
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201638/
https://www.ncbi.nlm.nih.gov/pubmed/32375749
http://dx.doi.org/10.1186/s12913-020-05246-x
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