The neonatal SCN2A mutant channel mimics adult channel properties

SCN2A mutations can cause early-onset epilepsy. Thompson et al. examined these human mutations in neonatal versus adult channel isoforms.

Detalles Bibliográficos
Autor principal: Muller, Grace K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201879/
https://www.ncbi.nlm.nih.gov/pubmed/32291436
http://dx.doi.org/10.1085/jgp.201912468
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author Muller, Grace K.
author_facet Muller, Grace K.
author_sort Muller, Grace K.
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description SCN2A mutations can cause early-onset epilepsy. Thompson et al. examined these human mutations in neonatal versus adult channel isoforms.
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spelling pubmed-72018792020-11-04 The neonatal SCN2A mutant channel mimics adult channel properties Muller, Grace K. J Gen Physiol Commentary SCN2A mutations can cause early-onset epilepsy. Thompson et al. examined these human mutations in neonatal versus adult channel isoforms. Rockefeller University Press 2020-04-14 /pmc/articles/PMC7201879/ /pubmed/32291436 http://dx.doi.org/10.1085/jgp.201912468 Text en © 2020 Muller http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentary
Muller, Grace K.
The neonatal SCN2A mutant channel mimics adult channel properties
title The neonatal SCN2A mutant channel mimics adult channel properties
title_full The neonatal SCN2A mutant channel mimics adult channel properties
title_fullStr The neonatal SCN2A mutant channel mimics adult channel properties
title_full_unstemmed The neonatal SCN2A mutant channel mimics adult channel properties
title_short The neonatal SCN2A mutant channel mimics adult channel properties
title_sort neonatal scn2a mutant channel mimics adult channel properties
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201879/
https://www.ncbi.nlm.nih.gov/pubmed/32291436
http://dx.doi.org/10.1085/jgp.201912468
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