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Depressed neuromuscular transmission causes weakness in mice lacking BK potassium channels
Mice lacking functional large-conductance voltage- and Ca(2+)-activated K(+) channels (BK channels) are viable but have motor deficits including ataxia and weakness. The cause of weakness is unknown. In this study, we discovered, in vivo, that skeletal muscle in mice lacking BK channels (BK(−/−)) wa...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201880/ https://www.ncbi.nlm.nih.gov/pubmed/32243496 http://dx.doi.org/10.1085/jgp.201912526 |