Cargando…
Intratumoral accumulation of gut microbiota facilitates CD47-based immunotherapy via STING signaling
Most studies focus on how intestinal microbiota influence cancer immunotherapy through activating gut immunity. However, immunotherapies related to innate responses such as CD47 blockade rely on the rapid immune responses within the tumor microenvironment. Using one defined anaerobic gut microbiota...
Autores principales: | Shi, Yaoyao, Zheng, Wenxin, Yang, Kaiting, Harris, Katharine G., Ni, Kaiyuan, Xue, Lai, Lin, Wenbin, Chang, Eugene B., Weichselbaum, Ralph R., Fu, Yang-Xin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201921/ https://www.ncbi.nlm.nih.gov/pubmed/32142585 http://dx.doi.org/10.1084/jem.20192282 |
Ejemplares similares
-
Suppression of local type I interferon by gut microbiota–derived butyrate impairs antitumor effects of ionizing radiation
por: Yang, Kaiting, et al.
Publicado: (2021) -
CD47 blockade enhances the efficacy of intratumoral STING-targeting therapy by activating phagocytes
por: Kosaka, Akemi, et al.
Publicado: (2021) -
Intratumoral administration of STING-activating nanovaccine enhances T cell immunotherapy
por: Jiang, Xiaoyi, et al.
Publicado: (2022) -
Correction: Intratumoral administration of STING-activating nanovaccine enhances T cell immunotherapy
Publicado: (2022) -
Lactobacillus rhamnosus GG induces cGAS/STING- dependent type I interferon and improves response to immune checkpoint blockade
por: Si, Wei, et al.
Publicado: (2022)