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Challenges of CAR- and TCR-T cell–based therapy for chronic infections
While therapy with T cells engineered with a chimeric antigen receptor (CAR) or a classical T cell receptor (TCR) is revolutionizing cancer treatment, its adoption in infectious diseases has been met with considerable resistance. Can we find its value for the cure of infections?
Autores principales: | Bertoletti, Antonio, Tan, Anthony Tanoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201928/ https://www.ncbi.nlm.nih.gov/pubmed/32163104 http://dx.doi.org/10.1084/jem.20191663 |
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