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Use of genetic variation to separate the effects of early and later life adiposity on disease risk: mendelian randomisation study
OBJECTIVE: To evaluate whether body size in early life has an independent effect on risk of disease in later life or whether its influence is mediated by body size in adulthood. DESIGN: Two sample univariable and multivariable mendelian randomisation. SETTING: The UK Biobank prospective cohort study...
Autores principales: | Richardson, Tom G, Sanderson, Eleanor, Elsworth, Benjamin, Tilling, Kate, Davey Smith, George |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group Ltd.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201936/ https://www.ncbi.nlm.nih.gov/pubmed/32376654 http://dx.doi.org/10.1136/bmj.m1203 |
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