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Bis-benzylidine Piperidone RA190 treatment of hepatocellular carcinoma via binding RPN13 and inhibiting NF-κB signaling

BACKGROUND: According to GLOBOSCAN, hepatocellular carcinoma (HCC) claimed 782,000 lives in 2018. The tyrosine kinase inhibitor sofafenib is used to treat HCC, but new anticancer agents targeting different pathways are urgently needed to improve outcomes for patients with advanced disease. The aberr...

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Detalles Bibliográficos
Autores principales:	Soong, Ruey-Shyang, Anchoori, Ravi K., Roden, Richard B. S., Cho, Rou-Ling, Chen, Yi-Chan, Tseng, Sheng-Chieh, Huang, Yun-Li, Liao, Po-Cheng, Shyu, Yu-Chiau
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201939/ https://www.ncbi.nlm.nih.gov/pubmed/32375699 http://dx.doi.org/10.1186/s12885-020-06896-0

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