Loss of N-Glycanase 1 Alters Transcriptional and Translational Regulation in K562 Cell Lines

N-Glycanase 1 (NGLY1) deficiency is an ultra-rare, complex and devastating neuromuscular disease. Patients display multi-organ symptoms including developmental delays, movement disorders, seizures, constipation and lack of tear production. NGLY1 is a deglycosylating protein involved in the degradati...

Descripción completa

Detalles Bibliográficos
Autores principales: Mueller, William F., Jakob, Petra, Sun, Han, Clauder-Münster, Sandra, Ghidelli-Disse, Sonja, Ordonez, Diana, Boesche, Markus, Bantscheff, Marcus, Collier, Paul, Haase, Bettina, Benes, Vladimir, Paulsen, Malte, Sehr, Peter, Lewis, Joe, Drewes, Gerard, Steinmetz, Lars M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202010/
https://www.ncbi.nlm.nih.gov/pubmed/32265286
http://dx.doi.org/10.1534/g3.119.401031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202010/
https://www.ncbi.nlm.nih.gov/pubmed/32265286
http://dx.doi.org/10.1534/g3.119.401031

Ejemplares similares