A Caenorhabditis elegans Model for Integrating the Functions of Neuropsychiatric Risk Genes Identifies Components Required for Normal Dendritic Morphology

Analysis of patient-derived DNA samples has identified hundreds of variants that are likely involved in neuropsychiatric diseases such as autism spectrum disorder (ASD) and schizophrenia (SCZ). While these studies couple behavioral phenotypes to individual genotypes, the number and diversity of cand...

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Detalles Bibliográficos
Autores principales: Aguirre-Chen, Cristina, Stec, Natalia, Ramos, Olivia Mendivil, Kim, Nuri, Kramer, Melissa, McCarthy, Shane, Gillis, Jesse, McCombie, W. Richard, Hammell, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202017/
https://www.ncbi.nlm.nih.gov/pubmed/32132169
http://dx.doi.org/10.1534/g3.119.400925

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