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DAF-16 and SMK-1 Contribute to Innate Immunity During Adulthood in Caenorhabditis elegans
Aging is accompanied by a progressive decline in immune function termed “immunosenescence”. Deficient surveillance coupled with the impaired function of immune cells compromises host defense in older animals. The dynamic activity of regulatory modules that control immunity appears to underlie age-de...
Autores principales: | McHugh, Daniel R., Koumis, Elena, Jacob, Paul, Goldfarb, Jennifer, Schlaubitz-Garcia, Michelle, Bennani, Safae, Regan, Paul, Patel, Prem, Youngman, Matthew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202018/ https://www.ncbi.nlm.nih.gov/pubmed/32161087 http://dx.doi.org/10.1534/g3.120.401166 |
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