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Sirt4 Modulates Oxidative Metabolism and Sensitivity to Rapamycin Through Species-Dependent Phenotypes in Drosophila mtDNA Haplotypes

The endosymbiotic theory proposes that eukaryotes evolved from the symbiotic relationship between anaerobic (host) and aerobic prokaryotes. Through iterative genetic transfers, the mitochondrial and nuclear genomes coevolved, establishing the mitochondria as the hub of oxidative metabolism. To study...

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Detalles Bibliográficos
Autores principales: Sejour, Richard, Sanguino, Roger A., Mikolajczak, Monika, Ahmadi, Walishah, Villa-Cuesta, Eugenia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202034/
https://www.ncbi.nlm.nih.gov/pubmed/32152006
http://dx.doi.org/10.1534/g3.120.401174

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