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Clindamycin induced toxic epidermal necrolysis versus Staphylococcal scalded skin syndrome: a case report

Toxic epidermal necrolysis and Staphylococcal scalded skin syndrome (SSSS) are potentially life-threatening dermatological emergencies that present in a similar clinical fashion. Toxic epidermal necrolysis is typically triggered by anticonvulsant and other neurological medications and reports clinda...

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Autores principales: Davey, Matthew G, Birrane, John, Brennan, Michelle, Breen, David P, Laing, Mary E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202050/
https://www.ncbi.nlm.nih.gov/pubmed/32395254
http://dx.doi.org/10.1093/omcr/omaa020
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author Davey, Matthew G
Birrane, John
Brennan, Michelle
Breen, David P
Laing, Mary E
author_facet Davey, Matthew G
Birrane, John
Brennan, Michelle
Breen, David P
Laing, Mary E
author_sort Davey, Matthew G
collection PubMed
description Toxic epidermal necrolysis and Staphylococcal scalded skin syndrome (SSSS) are potentially life-threatening dermatological emergencies that present in a similar clinical fashion. Toxic epidermal necrolysis is typically triggered by anticonvulsant and other neurological medications and reports clindamycin inducing the disease is exceedingly rare. SSSS seldomly occurs in adult patients. We present the case of a 60-year-old male presenting with dermatological rash covering >80% his body surface. Diagnosis and therapy involved multidisciplinary contribution from medical physicians, dermatologists, microbiologists and histopathologists to provide a favourable outcome.
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spelling pubmed-72020502020-05-11 Clindamycin induced toxic epidermal necrolysis versus Staphylococcal scalded skin syndrome: a case report Davey, Matthew G Birrane, John Brennan, Michelle Breen, David P Laing, Mary E Oxf Med Case Reports Case Report Toxic epidermal necrolysis and Staphylococcal scalded skin syndrome (SSSS) are potentially life-threatening dermatological emergencies that present in a similar clinical fashion. Toxic epidermal necrolysis is typically triggered by anticonvulsant and other neurological medications and reports clindamycin inducing the disease is exceedingly rare. SSSS seldomly occurs in adult patients. We present the case of a 60-year-old male presenting with dermatological rash covering >80% his body surface. Diagnosis and therapy involved multidisciplinary contribution from medical physicians, dermatologists, microbiologists and histopathologists to provide a favourable outcome. Oxford University Press 2020-05-06 /pmc/articles/PMC7202050/ /pubmed/32395254 http://dx.doi.org/10.1093/omcr/omaa020 Text en © The Author(s) 2020. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Davey, Matthew G
Birrane, John
Brennan, Michelle
Breen, David P
Laing, Mary E
Clindamycin induced toxic epidermal necrolysis versus Staphylococcal scalded skin syndrome: a case report
title Clindamycin induced toxic epidermal necrolysis versus Staphylococcal scalded skin syndrome: a case report
title_full Clindamycin induced toxic epidermal necrolysis versus Staphylococcal scalded skin syndrome: a case report
title_fullStr Clindamycin induced toxic epidermal necrolysis versus Staphylococcal scalded skin syndrome: a case report
title_full_unstemmed Clindamycin induced toxic epidermal necrolysis versus Staphylococcal scalded skin syndrome: a case report
title_short Clindamycin induced toxic epidermal necrolysis versus Staphylococcal scalded skin syndrome: a case report
title_sort clindamycin induced toxic epidermal necrolysis versus staphylococcal scalded skin syndrome: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202050/
https://www.ncbi.nlm.nih.gov/pubmed/32395254
http://dx.doi.org/10.1093/omcr/omaa020
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