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Mrx6 regulates mitochondrial DNA copy number in Saccharomyces cerevisiae by engaging the evolutionarily conserved Lon protease Pim1

Mitochondrial function depends crucially on the maintenance of multiple mitochondrial DNA (mtDNA) copies. Surprisingly, the cellular mechanisms regulating mtDNA copy number remain poorly understood. Through a systematic high-throughput approach in Saccharomyces cerevisiae, we determined mtDNA–to–nuc...

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Detalles Bibliográficos
Autores principales:	Göke, Aylin, Schrott, Simon, Mizrak, Arda, Belyy, Vladislav, Osman, Christof, Walter, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202074/ https://www.ncbi.nlm.nih.gov/pubmed/31532710 http://dx.doi.org/10.1091/mbc.E19-08-0470

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