Heme oxygenase-1 inhibition mediates Gas6 to enhance bortezomib-sensitivity in multiple myeloma via ERK/STAT3 axis

Chemoresistance is still a critical challenge for efficient treatment of multiple myeloma (MM) during the bortezomib-based chemotherapy. Recent studies have suggested that heme oxygenase-1 (HO-1) is involved in apoptosis, proliferation and chemoresistance in cancer cells. Here we aim to investigate...

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Detalles Bibliográficos
Autores principales: Zhang, Zhaoyuan, Wang, Weili, Ma, Dan, Xiong, Jie, Kuang, Xingyi, Zhang, Siyu, Fang, Qin, Wang, Jishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202511/
https://www.ncbi.nlm.nih.gov/pubmed/32298237
http://dx.doi.org/10.18632/aging.102996

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