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Epigenetic modulation of macrophage polarization prevents lumbar disc degeneration

Inflammation plays an essential role in the development of lumbar disc degeneration (LDD), although the exact effects of macrophage subtypes on LDD remain unclear. Based on previous studies, we hypothesized that M2-polarization of local macrophages and simultaneous suppression of their production of...

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Detalles Bibliográficos
Autores principales: Hou, Yang, Shi, Guodong, Guo, Yongfei, Shi, Jiangang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202517/
https://www.ncbi.nlm.nih.gov/pubmed/32310825
http://dx.doi.org/10.18632/aging.102909