Cargando…

Toward Development of a Vocal Fold Contact Pressure Probe: Sensor Characterization and Validation Using Synthetic Vocal Fold Models

Excessive vocal fold collision pressures during phonation are considered to play a primary role in the formation of benign vocal fold lesions, such as nodules. The ability to accurately and reliably acquire intraglottal pressure has the potential to provide unique insights into the pathophysiology o...

Descripción completa

Detalles Bibliográficos
Autores principales: Motie-Shirazi, Mohsen, Zañartu, Matías, Peterson, Sean D., Mehta, Daryush D., Kobler, James B., Hillman, Robert E., Erath, Byron D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202565/
https://www.ncbi.nlm.nih.gov/pubmed/32377408
http://dx.doi.org/10.3390/app9153002
_version_ 1783529723558625280
author Motie-Shirazi, Mohsen
Zañartu, Matías
Peterson, Sean D.
Mehta, Daryush D.
Kobler, James B.
Hillman, Robert E.
Erath, Byron D.
author_facet Motie-Shirazi, Mohsen
Zañartu, Matías
Peterson, Sean D.
Mehta, Daryush D.
Kobler, James B.
Hillman, Robert E.
Erath, Byron D.
author_sort Motie-Shirazi, Mohsen
collection PubMed
description Excessive vocal fold collision pressures during phonation are considered to play a primary role in the formation of benign vocal fold lesions, such as nodules. The ability to accurately and reliably acquire intraglottal pressure has the potential to provide unique insights into the pathophysiology of phonotrauma. Difficulties arise, however, in directly measuring vocal fold contact pressures due to physical intrusion from the sensor that may disrupt the contact mechanics, as well as difficulty in determining probe/sensor position relative to the contact location. These issues are quantified and addressed through the implementation of a novel approach for identifying the timing and location of vocal fold contact, and measuring intraglottal and vocal fold contact pressures via a pressure probe embedded in the wall of a hemi-laryngeal flow facility. The accuracy and sensitivity of the pressure measurements are validated against ground truth values. Application to in vivo approaches are assessed by acquiring intraglottal and VF contact pressures using a synthetic, self-oscillating vocal fold model in a hemi-laryngeal configuration, where the sensitivity of the measured intraglottal and vocal fold contact pressure relative to the sensor position is explored.
format Online
Article
Text
id pubmed-7202565
institution National Center for Biotechnology Information
language English
publishDate 2019
record_format MEDLINE/PubMed
spelling pubmed-72025652020-08-01 Toward Development of a Vocal Fold Contact Pressure Probe: Sensor Characterization and Validation Using Synthetic Vocal Fold Models Motie-Shirazi, Mohsen Zañartu, Matías Peterson, Sean D. Mehta, Daryush D. Kobler, James B. Hillman, Robert E. Erath, Byron D. Appl Sci (Basel) Article Excessive vocal fold collision pressures during phonation are considered to play a primary role in the formation of benign vocal fold lesions, such as nodules. The ability to accurately and reliably acquire intraglottal pressure has the potential to provide unique insights into the pathophysiology of phonotrauma. Difficulties arise, however, in directly measuring vocal fold contact pressures due to physical intrusion from the sensor that may disrupt the contact mechanics, as well as difficulty in determining probe/sensor position relative to the contact location. These issues are quantified and addressed through the implementation of a novel approach for identifying the timing and location of vocal fold contact, and measuring intraglottal and vocal fold contact pressures via a pressure probe embedded in the wall of a hemi-laryngeal flow facility. The accuracy and sensitivity of the pressure measurements are validated against ground truth values. Application to in vivo approaches are assessed by acquiring intraglottal and VF contact pressures using a synthetic, self-oscillating vocal fold model in a hemi-laryngeal configuration, where the sensitivity of the measured intraglottal and vocal fold contact pressure relative to the sensor position is explored. 2019-07-26 2019-08 /pmc/articles/PMC7202565/ /pubmed/32377408 http://dx.doi.org/10.3390/app9153002 Text en Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Motie-Shirazi, Mohsen
Zañartu, Matías
Peterson, Sean D.
Mehta, Daryush D.
Kobler, James B.
Hillman, Robert E.
Erath, Byron D.
Toward Development of a Vocal Fold Contact Pressure Probe: Sensor Characterization and Validation Using Synthetic Vocal Fold Models
title Toward Development of a Vocal Fold Contact Pressure Probe: Sensor Characterization and Validation Using Synthetic Vocal Fold Models
title_full Toward Development of a Vocal Fold Contact Pressure Probe: Sensor Characterization and Validation Using Synthetic Vocal Fold Models
title_fullStr Toward Development of a Vocal Fold Contact Pressure Probe: Sensor Characterization and Validation Using Synthetic Vocal Fold Models
title_full_unstemmed Toward Development of a Vocal Fold Contact Pressure Probe: Sensor Characterization and Validation Using Synthetic Vocal Fold Models
title_short Toward Development of a Vocal Fold Contact Pressure Probe: Sensor Characterization and Validation Using Synthetic Vocal Fold Models
title_sort toward development of a vocal fold contact pressure probe: sensor characterization and validation using synthetic vocal fold models
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202565/
https://www.ncbi.nlm.nih.gov/pubmed/32377408
http://dx.doi.org/10.3390/app9153002
work_keys_str_mv AT motieshirazimohsen towarddevelopmentofavocalfoldcontactpressureprobesensorcharacterizationandvalidationusingsyntheticvocalfoldmodels
AT zanartumatias towarddevelopmentofavocalfoldcontactpressureprobesensorcharacterizationandvalidationusingsyntheticvocalfoldmodels
AT petersonseand towarddevelopmentofavocalfoldcontactpressureprobesensorcharacterizationandvalidationusingsyntheticvocalfoldmodels
AT mehtadaryushd towarddevelopmentofavocalfoldcontactpressureprobesensorcharacterizationandvalidationusingsyntheticvocalfoldmodels
AT koblerjamesb towarddevelopmentofavocalfoldcontactpressureprobesensorcharacterizationandvalidationusingsyntheticvocalfoldmodels
AT hillmanroberte towarddevelopmentofavocalfoldcontactpressureprobesensorcharacterizationandvalidationusingsyntheticvocalfoldmodels
AT erathbyrond towarddevelopmentofavocalfoldcontactpressureprobesensorcharacterizationandvalidationusingsyntheticvocalfoldmodels