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Engineering a 3D in vitro model of human skeletal muscle at the single fiber scale

The reproduction of reliable in vitro models of human skeletal muscle is made harder by the intrinsic 3D structural complexity of this tissue. Here we coupled engineered hydrogel with 3D structural cues and specific mechanical properties to derive human 3D muscle constructs (“myobundles”) at the sca...

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Detalles Bibliográficos
Autores principales: Urciuolo, Anna, Serena, Elena, Ghua, Rusha, Zatti, Susi, Giomo, Monica, Mattei, Nicolò, Vetralla, Massimo, Selmin, Giulia, Luni, Camilla, Vitulo, Nicola, Valle, Giorgio, Vitiello, Libero, Elvassore, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202609/
https://www.ncbi.nlm.nih.gov/pubmed/32374763
http://dx.doi.org/10.1371/journal.pone.0232081