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Leptin signaling and the intervertebral disc: Sex dependent effects of leptin receptor deficiency and Western diet on the spine in a type 2 diabetes mouse model
Type 2 diabetes and obesity are associated with back pain in juveniles and adults and are implicated in intervertebral disc (IVD) degeneration. Hypercaloric Western diets are associated with both obesity and type 2 diabetes. The objective of this study was to determine if obesity and type 2 diabetes...
Autores principales: | Natelson, Devorah M., Lai, Alon, Krishnamoorthy, Divya, Hoy, Robert C., Iatridis, James C., Illien-Jünger, Svenja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202633/ https://www.ncbi.nlm.nih.gov/pubmed/32374776 http://dx.doi.org/10.1371/journal.pone.0227527 |
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