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Both male and female obese ZSF1 rats develop cardiac dysfunction in obesity-induced heart failure with preserved ejection fraction
Heart failure with a preserved ejection fraction (HFpEF) is associated with multiple comorbidities, such as old age, hypertension, type 2 diabetes and obesity and is more prevalent in females. Although the male obese ZSF1 rat has been proposed as a suitable model to study the development of diastoli...
Autores principales: | Nguyen, Isabel T. N., Brandt, Maarten M., van de Wouw, Jens, van Drie, Ruben W. A., Wesseling, Marian, Cramer, Maarten J., de Jager, Saskia C. A., Merkus, Daphne, Duncker, Dirk J., Cheng, Caroline, Joles, Jaap. A., Verhaar, Marianne C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202634/ https://www.ncbi.nlm.nih.gov/pubmed/32374790 http://dx.doi.org/10.1371/journal.pone.0232399 |
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