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RIG-I-like receptor activation drives type I IFN and antiviral signaling to limit Hantaan orthohantavirus replication

Pathogenic hantaviruses, genus Orthohantaviridae, are maintained in rodent reservoirs with zoonotic transmission to humans occurring through inhalation of rodent excreta. Hantavirus disease in humans is characterized by localized vascular leakage and elevated levels of circulating proinflammatory cy...

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Detalles Bibliográficos
Autores principales:	Kell, Alison M., Hemann, Emily A., Turnbull, J. Bryan, Gale, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202661/ https://www.ncbi.nlm.nih.gov/pubmed/32330200 http://dx.doi.org/10.1371/journal.ppat.1008483

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