Translesion synthesis polymerases are dispensable for C. elegans reproduction but suppress genome scarring by polymerase theta-mediated end joining

Bases within DNA are frequently damaged, producing obstacles to efficient and accurate DNA replication by replicative polymerases. Translesion synthesis (TLS) polymerases, via their ability to catalyze nucleotide additions to growing DNA chains across DNA lesions, promote replication of damaged DNA,...

Descripción completa

Detalles Bibliográficos
Autores principales: van Bostelen, Ivo, van Schendel, Robin, Romeijn, Ron, Tijsterman, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202663/
https://www.ncbi.nlm.nih.gov/pubmed/32330130
http://dx.doi.org/10.1371/journal.pgen.1008759

Ejemplares similares

Ejemplares similares