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Epithelium intrinsic vitamin A signaling co-ordinates pathogen clearance in the gut via IL-18
Intestinal epithelial cells (IECs) are at the forefront of host-pathogen interactions, coordinating a cascade of immune responses to protect against pathogens. Here we show that IEC-intrinsic vitamin A signaling restricts pathogen invasion early in the infection and subsequently activates immune cel...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202665/ https://www.ncbi.nlm.nih.gov/pubmed/32330185 http://dx.doi.org/10.1371/journal.ppat.1008360 |