Imiquimod suppresses respiratory syncytial virus (RSV) replication via PKA pathway and reduces RSV induced-inflammation and viral load in mice lungs

Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract disease and bronchiolitis in children, as well as an important cause of morbidity and mortality in elderly and immunocompromised individuals. However, there is no safe and efficacious RSV vaccine or antiviral treatment....

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Detalles Bibliográficos
Autores principales: Salinas, Franco Maximiliano, Nebreda, Antonela Díaz, Vázquez, Luciana, Gentilini, María Virginia, Marini, Victoria, Benedetti, Martina, Nabaes Jodar, Mercedes Soledad, Viegas, Mariana, Shayo, Carina, Bueno, Carlos Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202858/
https://www.ncbi.nlm.nih.gov/pubmed/32387475
http://dx.doi.org/10.1016/j.antiviral.2020.104817

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