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Axonal Na(+) channels detect and transmit levels of input synchrony in local brain circuits

Sensory processing requires mechanisms of fast coincidence detection to discriminate synchronous from asynchronous inputs. Spike threshold adaptation enables such a discrimination but is ineffective in transmitting this information to the network. We show here that presynaptic axonal sodium channels...

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Detalles Bibliográficos
Autores principales: Zbili, Mickaël, Rama, Sylvain, Yger, Pierre, Inglebert, Yanis, Boumedine-Guignon, Norah, Fronzaroli-Moliniere, Laure, Brette, Romain, Russier, Michaël, Debanne, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202877/
https://www.ncbi.nlm.nih.gov/pubmed/32494697
http://dx.doi.org/10.1126/sciadv.aay4313