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Chromatin Is Frequently Unknotted at the Megabase Scale
Knots in the human genome would greatly impact diverse cellular processes ranging from transcription to gene regulation. To date, it has not been possible to directly examine the genome in vivo for the presence of knots. Recently, methods for serial fluorescent in situ hybridization have made it pos...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Biophysical Society
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202934/ https://www.ncbi.nlm.nih.gov/pubmed/31818464 http://dx.doi.org/10.1016/j.bpj.2019.11.002 |