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A Penicillium rubens platform strain for secondary metabolite production

We present a Penicillium rubens strain with an industrial background in which the four highly expressed biosynthetic gene clusters (BGC) required to produce penicillin, roquefortine, chrysogine and fungisporin were removed. This resulted in a minimal secondary metabolite background. Amino acid pools...

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Detalles Bibliográficos
Autores principales:	Pohl, Carsten, Polli, Fabiola, Schütze, Tabea, Viggiano, Annarita, Mózsik, László, Jung, Sascha, de Vries, Maaike, Bovenberg, Roel A. L., Meyer, Vera, Driessen, Arnold J. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203126/ https://www.ncbi.nlm.nih.gov/pubmed/32376967 http://dx.doi.org/10.1038/s41598-020-64893-6

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