Knocking-down of the Prokineticin receptor 2 affects reveals its complex role in the regulation of the hypothalamus-pituitary-gonadal axis in the zebrafish model

Prokineticin receptors (PROKR1 and PROKR2) are G protein-coupled receptors which control human central and peripheral reproductive processes. Importantly, allelic variants of PROKR2 in humans are associated with altered migration of GnRH neurons, resulting in congenital hypogonadotropic hypogonadism...

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Detalles Bibliográficos
Autores principales: Bassi, Ivan, Luzzani, Francesca, Marelli, Federica, Vezzoli, Valeria, Cotellessa, Ludovica, Prober, David A., Persani, Luca, Gothilf, Yoav, Bonomi, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203128/
https://www.ncbi.nlm.nih.gov/pubmed/32376893
http://dx.doi.org/10.1038/s41598-020-64077-2

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