Cargando…

Deep Learning-based Inaccuracy Compensation in Reconstruction of High Resolution XCT Data

While X-ray computed tomography (XCT) is pushed further into the micro- and nanoscale, the limitations of various tool components and object motion become more apparent. For high-resolution XCT, it is necessary but practically difficult to align these tool components with sub-micron precision. The a...

Descripción completa

Detalles Bibliográficos
Autores principales: Topal, Emre, Löffler, Markus, Zschech, Ehrenfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203197/
https://www.ncbi.nlm.nih.gov/pubmed/32376852
http://dx.doi.org/10.1038/s41598-020-64733-7
_version_ 1783529833236529152
author Topal, Emre
Löffler, Markus
Zschech, Ehrenfried
author_facet Topal, Emre
Löffler, Markus
Zschech, Ehrenfried
author_sort Topal, Emre
collection PubMed
description While X-ray computed tomography (XCT) is pushed further into the micro- and nanoscale, the limitations of various tool components and object motion become more apparent. For high-resolution XCT, it is necessary but practically difficult to align these tool components with sub-micron precision. The aim is to develop a novel reconstruction methodology that considers unavoidable misalignment and object motion during the data acquisition in order to obtain high-quality three-dimensional images and that is applicable for data recovery from incomplete datasets. A reconstruction software empowered by sophisticated correction modules that autonomously estimates and compensates artefacts using gradient descent and deep learning algorithms has been developed and applied. For motion estimation, a novel computer vision methodology coupled with a deep convolutional neural network approach provides estimates for the object motion by tracking features throughout the adjacent projections. The model is trained using the forward projections of simulated phantoms that consist of several simple geometrical features such as sphere, triangle and rectangular. The feature maps extracted by a neural network are used to detect and to classify features done by a support vector machine. For missing data recovery, a novel deep convolutional neural network is used to infer high-quality reconstruction data from incomplete sets of projections. The forward and back projections of simulated geometric shapes from a range of angular ranges are used to train the model. The model is able to learn the angular dependency based on a limited angle coverage and to propose a new set of projections to suppress artefacts. High-quality three-dimensional images demonstrate that it is possible to effectively suppress artefacts caused by thermomechanical instability of tool components and objects resulting in motion, by center of rotation misalignment and by inaccuracy in the detector position without additional computational efforts. Data recovery from incomplete sets of projections result in directly corrected projections instead of suppressing artefacts in the final reconstructed images. The proposed methodology has been proven and is demonstrated for a ball bearing sample. The reconstruction results are compared to prior corrections and benchmarked with a commercially available reconstruction software. Compared to conventional approaches in XCT imaging and data analysis, the proposed methodology for the generation of high-quality three-dimensional X-ray images is fully autonomous. The methodology presented here has been proven for high-resolution micro-XCT and nano-XCT, however, is applicable for all length scales.
format Online
Article
Text
id pubmed-7203197
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-72031972020-05-15 Deep Learning-based Inaccuracy Compensation in Reconstruction of High Resolution XCT Data Topal, Emre Löffler, Markus Zschech, Ehrenfried Sci Rep Article While X-ray computed tomography (XCT) is pushed further into the micro- and nanoscale, the limitations of various tool components and object motion become more apparent. For high-resolution XCT, it is necessary but practically difficult to align these tool components with sub-micron precision. The aim is to develop a novel reconstruction methodology that considers unavoidable misalignment and object motion during the data acquisition in order to obtain high-quality three-dimensional images and that is applicable for data recovery from incomplete datasets. A reconstruction software empowered by sophisticated correction modules that autonomously estimates and compensates artefacts using gradient descent and deep learning algorithms has been developed and applied. For motion estimation, a novel computer vision methodology coupled with a deep convolutional neural network approach provides estimates for the object motion by tracking features throughout the adjacent projections. The model is trained using the forward projections of simulated phantoms that consist of several simple geometrical features such as sphere, triangle and rectangular. The feature maps extracted by a neural network are used to detect and to classify features done by a support vector machine. For missing data recovery, a novel deep convolutional neural network is used to infer high-quality reconstruction data from incomplete sets of projections. The forward and back projections of simulated geometric shapes from a range of angular ranges are used to train the model. The model is able to learn the angular dependency based on a limited angle coverage and to propose a new set of projections to suppress artefacts. High-quality three-dimensional images demonstrate that it is possible to effectively suppress artefacts caused by thermomechanical instability of tool components and objects resulting in motion, by center of rotation misalignment and by inaccuracy in the detector position without additional computational efforts. Data recovery from incomplete sets of projections result in directly corrected projections instead of suppressing artefacts in the final reconstructed images. The proposed methodology has been proven and is demonstrated for a ball bearing sample. The reconstruction results are compared to prior corrections and benchmarked with a commercially available reconstruction software. Compared to conventional approaches in XCT imaging and data analysis, the proposed methodology for the generation of high-quality three-dimensional X-ray images is fully autonomous. The methodology presented here has been proven for high-resolution micro-XCT and nano-XCT, however, is applicable for all length scales. Nature Publishing Group UK 2020-05-06 /pmc/articles/PMC7203197/ /pubmed/32376852 http://dx.doi.org/10.1038/s41598-020-64733-7 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Topal, Emre
Löffler, Markus
Zschech, Ehrenfried
Deep Learning-based Inaccuracy Compensation in Reconstruction of High Resolution XCT Data
title Deep Learning-based Inaccuracy Compensation in Reconstruction of High Resolution XCT Data
title_full Deep Learning-based Inaccuracy Compensation in Reconstruction of High Resolution XCT Data
title_fullStr Deep Learning-based Inaccuracy Compensation in Reconstruction of High Resolution XCT Data
title_full_unstemmed Deep Learning-based Inaccuracy Compensation in Reconstruction of High Resolution XCT Data
title_short Deep Learning-based Inaccuracy Compensation in Reconstruction of High Resolution XCT Data
title_sort deep learning-based inaccuracy compensation in reconstruction of high resolution xct data
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203197/
https://www.ncbi.nlm.nih.gov/pubmed/32376852
http://dx.doi.org/10.1038/s41598-020-64733-7
work_keys_str_mv AT topalemre deeplearningbasedinaccuracycompensationinreconstructionofhighresolutionxctdata
AT lofflermarkus deeplearningbasedinaccuracycompensationinreconstructionofhighresolutionxctdata
AT zschechehrenfried deeplearningbasedinaccuracycompensationinreconstructionofhighresolutionxctdata