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Tolcapone Potently Inhibits Seminal Amyloid Fibrils Formation and Blocks Entry of Ebola Pseudoviruses

Ebola virus (EBOV), the causative pathogen of the deadly EBOV disease (EVD), can be transmitted via sexual transmission. Seminal amyloid fibrils have been found enhancers of EBOV infection. Currently, limited preventive vaccine or therapeutic is available to block EBOV infection through sexual inter...

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Detalles Bibliográficos
Autores principales: Qiu, Mengjie, Li, Zhaofeng, Chen, Yuliu, Guo, Jiayin, Xu, Wei, Qi, Tao, Qiu, Yurong, Pang, Jianxin, Li, Lin, Liu, Shuwen, Tan, Suiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203225/
https://www.ncbi.nlm.nih.gov/pubmed/32425892
http://dx.doi.org/10.3389/fmicb.2020.00504