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Genomic competition for noise reduction shaped evolutionary landscape of mir-4673
The genomic platform that informs evolution of microRNA cascades remains unknown. Here we capitalised on the recent evolutionary trajectory of hominin-specific miRNA-4673, encoded in intron 4 of notch-1, to uncover the identity of one such precursor genomic element and the selective forces acting up...
Autores principales: | Farahani, Ramin M., Rezaei-Lotfi, Saba, Hunter, Neil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203229/ https://www.ncbi.nlm.nih.gov/pubmed/32376854 http://dx.doi.org/10.1038/s41540-020-0131-2 |
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