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An Ex Vivo Brain Slice Culture Model of Chronic Wasting Disease: Implications for Disease Pathogenesis and Therapeutic Development

Chronic wasting disease (CWD) is a rapidly spreading prion disease of cervids, yet antemortem diagnosis, treatment, and control remain elusive. We recently developed an organotypic slice culture assay for sensitive detection of scrapie prions using ultrasensitive prion seeding. However, this model w...

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Detalles Bibliográficos
Autores principales:	Kondru, Naveen, Manne, Sireesha, Kokemuller, Robyn, Greenlee, Justin, Greenlee, M. Heather West, Nichols, Tracy, Kong, Qingzhong, Anantharam, Vellareddy, Kanthasamy, Arthi, Halbur, Patrick, Kanthasamy, Anumantha G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203233/ https://www.ncbi.nlm.nih.gov/pubmed/32376941 http://dx.doi.org/10.1038/s41598-020-64456-9

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