Potential SARS-CoV-2 Preimmune IgM Epitopes

While studying the human public IgM igome as represented by a library of 224,087 linear mimotopes, three exact matches to peptides in the proteins of SARS-CoV-2 were found: two in the open reading frame 1ab and one in the spike protein. Joining the efforts to fast track SARS-CoV-2 vaccine developmen...

Descripción completa

Detalles Bibliográficos
Autores principales: Shivarov, Velizar, Petrov, Peter K., Pashov, Anastas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203467/
https://www.ncbi.nlm.nih.gov/pubmed/32425955
http://dx.doi.org/10.3389/fimmu.2020.00932
_version_ 1783529875775160320
author Shivarov, Velizar
Petrov, Peter K.
Pashov, Anastas D.
author_facet Shivarov, Velizar
Petrov, Peter K.
Pashov, Anastas D.
author_sort Shivarov, Velizar
collection PubMed
description While studying the human public IgM igome as represented by a library of 224,087 linear mimotopes, three exact matches to peptides in the proteins of SARS-CoV-2 were found: two in the open reading frame 1ab and one in the spike protein. Joining the efforts to fast track SARS-CoV-2 vaccine development, here we describe briefly these potential epitopes in comparison to mimotopes representing peptides of SARS-CoV, HCoV 229E and OC43.
format Online
Article
Text
id pubmed-7203467
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-72034672020-05-18 Potential SARS-CoV-2 Preimmune IgM Epitopes Shivarov, Velizar Petrov, Peter K. Pashov, Anastas D. Front Immunol Immunology While studying the human public IgM igome as represented by a library of 224,087 linear mimotopes, three exact matches to peptides in the proteins of SARS-CoV-2 were found: two in the open reading frame 1ab and one in the spike protein. Joining the efforts to fast track SARS-CoV-2 vaccine development, here we describe briefly these potential epitopes in comparison to mimotopes representing peptides of SARS-CoV, HCoV 229E and OC43. Frontiers Media S.A. 2020-04-30 /pmc/articles/PMC7203467/ /pubmed/32425955 http://dx.doi.org/10.3389/fimmu.2020.00932 Text en Copyright © 2020 Shivarov, Petrov and Pashov. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Shivarov, Velizar
Petrov, Peter K.
Pashov, Anastas D.
Potential SARS-CoV-2 Preimmune IgM Epitopes
title Potential SARS-CoV-2 Preimmune IgM Epitopes
title_full Potential SARS-CoV-2 Preimmune IgM Epitopes
title_fullStr Potential SARS-CoV-2 Preimmune IgM Epitopes
title_full_unstemmed Potential SARS-CoV-2 Preimmune IgM Epitopes
title_short Potential SARS-CoV-2 Preimmune IgM Epitopes
title_sort potential sars-cov-2 preimmune igm epitopes
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203467/
https://www.ncbi.nlm.nih.gov/pubmed/32425955
http://dx.doi.org/10.3389/fimmu.2020.00932
work_keys_str_mv AT shivarovvelizar potentialsarscov2preimmuneigmepitopes
AT petrovpeterk potentialsarscov2preimmuneigmepitopes
AT pashovanastasd potentialsarscov2preimmuneigmepitopes

Ejemplares similares